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Identification of Neutralizing Monoclonal Antibodies Targeting Novel Conformational Epitopes of the Porcine Epidemic Diarrhoea Virus Spike Protein

Since 2010, newly identified variants of porcine epidemic diarrhoea virus (PEDV) have caused high mortality in neonatal piglets which has devastated the swine industry. The spike (S) glycoprotein of PEDV contains multiple neutralizing epitopes and is a major target for PEDV neutralization and vaccin...

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Detalles Bibliográficos
Autores principales: Chang, Chia-Yu, Cheng, Ivan-Chen, Chang, Yen-Chen, Tsai, Pei-Shiue, Lai, Seiu-Yu, Huang, Yu-Liang, Jeng, Chian-Ren, Pang, Victor Fei, Chang, Hui-Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6385244/
https://www.ncbi.nlm.nih.gov/pubmed/30792462
http://dx.doi.org/10.1038/s41598-019-39844-5