Dynamic Effects of CYP2D6 Genetic Variants in a Set of Poor Metaboliser Patients with Infiltrating Ductal Cancer Under Treatment with Tamoxifen

Breast cancer is a group of multigenic diseases. It is the most common cancer diagnosed among women worldwide and is often treated with tamoxifen. Tamoxifen is catalysed by cytochrome P450 2D6 (CYP2D6), and inter-individual variations in the enzyme due to single nucleotide polymorphisms (SNPs) could...

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Detalles Bibliográficos
Autores principales: Ariza Márquez, Yeimy Viviana, Briceño, Ignacio, Aristizábal, Fabio, Niño, Luis Fernando, Yosa Reyes, Juvenal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6385267/
https://www.ncbi.nlm.nih.gov/pubmed/30792473
http://dx.doi.org/10.1038/s41598-018-38340-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6385267/
https://www.ncbi.nlm.nih.gov/pubmed/30792473
http://dx.doi.org/10.1038/s41598-018-38340-6

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