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COA-Cl (2-Cl-C.OXT-A) can promote coronary collateral development following acute myocardial infarction in mice

2-Cl-C.OXT-A (COA-Cl) is a novel nucleic acid analogue that promotes tube-forming activity of human umbilical vein endothelial cells (HUVEC) through vascular endothelial growth factor (VEGF). The development of coronary collateral circulation is critical to rescue the ischemic myocardium and to prev...

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Detalles Bibliográficos
Autores principales: Nishikido, Toshiyuki, Oyama, Jun-ichi, Shiraki, Aya, Tsukamoto, Ikuko, Igarashi, Junsuke, Node, Koichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6385273/
https://www.ncbi.nlm.nih.gov/pubmed/30796271
http://dx.doi.org/10.1038/s41598-019-39222-1