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COA-Cl (2-Cl-C.OXT-A) can promote coronary collateral development following acute myocardial infarction in mice
2-Cl-C.OXT-A (COA-Cl) is a novel nucleic acid analogue that promotes tube-forming activity of human umbilical vein endothelial cells (HUVEC) through vascular endothelial growth factor (VEGF). The development of coronary collateral circulation is critical to rescue the ischemic myocardium and to prev...
Autores principales: | Nishikido, Toshiyuki, Oyama, Jun-ichi, Shiraki, Aya, Tsukamoto, Ikuko, Igarashi, Junsuke, Node, Koichi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6385273/ https://www.ncbi.nlm.nih.gov/pubmed/30796271 http://dx.doi.org/10.1038/s41598-019-39222-1 |
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