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Higher CXCL16 exodomain is associated with aggressive ovarian cancer and promotes the disease by CXCR6 activation and MMP modulation

Ovarian cancer (OvCa) is the leading cause of death from gynecological malignancies. Five-year survival rate of OvCa ranges from 30–92%, depending on the spread of disease at diagnosis. Role of chemokines is well appreciated in cancer, including OvCa. However, their precise role is understudied. Her...

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Detalles Bibliográficos
Autores principales: Mir, Hina, Kaur, Gurpreet, Kapur, Neeraj, Bae, Sejong, Lillard, James W., Singh, Shailesh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6385302/
https://www.ncbi.nlm.nih.gov/pubmed/30792527
http://dx.doi.org/10.1038/s41598-019-38766-6