Irreversible electroporation reverses resistance to immune checkpoint blockade in pancreatic cancer

Immunotherapy has only limited efficacy against pancreatic ductal adenocarcinoma (PDAC) due to the presence of an immunosuppressive tumor-associated stroma. Here, we demonstrate an effective modulation of that stroma by irreversible electroporation (IRE), a local ablation technique that has received...

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Detalles Bibliográficos
Autores principales: Zhao, Jun, Wen, Xiaofei, Tian, Li, Li, Tingting, Xu, Chunyu, Wen, Xiaoxia, Melancon, Marites P., Gupta, Sanjay, Shen, Baozhong, Peng, Weiyi, Li, Chun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6385305/
https://www.ncbi.nlm.nih.gov/pubmed/30796212
http://dx.doi.org/10.1038/s41467-019-08782-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6385305/
https://www.ncbi.nlm.nih.gov/pubmed/30796212
http://dx.doi.org/10.1038/s41467-019-08782-1

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