Retrograde transport of Akt by a neuronal Rab5-APPL1 endosome

Long-distance axonal trafficking plays a critical role in neuronal function and transport defects have been linked to neurodegenerative disorders. Various lines of evidence suggest that the small GTPase Rab5 plays a role in neuronal signaling via early endosomal transport. Here, we characterized the...

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Detalles Bibliográficos
Autores principales: Goto-Silva, Livia, McShane, Marisa P., Salinas, Sara, Kalaidzidis, Yannis, Schiavo, Giampietro, Zerial, Marino
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6385319/
https://www.ncbi.nlm.nih.gov/pubmed/30792402
http://dx.doi.org/10.1038/s41598-019-38637-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6385319/
https://www.ncbi.nlm.nih.gov/pubmed/30792402
http://dx.doi.org/10.1038/s41598-019-38637-0

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