Alectinib in the treatment of ALK-positive metastatic non-small cell lung cancer: clinical trial evidence and experience with a focus on brain metastases

Molecular profiling of metastatic nonsquamous non-small cell lung cancer (NSCLC) is required to guide the treatment strategy. Anaplastic lymphoma kinase (ALK) gene rearrangements are found in approximately 5% of lung adenocarcinomas and are associated with specific clinical features including a high...

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Detalles Bibliográficos
Autores principales: Tomasini, Pascale, Egea, Julie, Souquet-Bressand, Maxime, Greillier, Laurent, Barlesi, Fabrice
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2019
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6385324/
https://www.ncbi.nlm.nih.gov/pubmed/30786826
http://dx.doi.org/10.1177/1753466619831906

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6385324/
https://www.ncbi.nlm.nih.gov/pubmed/30786826
http://dx.doi.org/10.1177/1753466619831906

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