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Site-specific chelation therapy with EDTA-loaded albumin nanoparticles reverses arterial calcification in a rat model of chronic kidney disease

Medial arterial calcification (MAC) is a common outcome in diabetes and chronic kidney disease (CKD). It occurs as linear mineral deposits along the degraded elastin lamellae and is responsible for increased aortic stiffness and subsequent cardiovascular events. Current treatments for calcification,...

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Detalles Bibliográficos
Autores principales: Karamched, Saketh R., Nosoudi, Nasim, Moreland, Hannah E., Chowdhury, Aniqa, Vyavahare, Naren R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6385348/
https://www.ncbi.nlm.nih.gov/pubmed/30796300
http://dx.doi.org/10.1038/s41598-019-39639-8