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Distribution of insulin in trigeminal nerve and brain after intranasal administration

In the brain, insulin acts as a growth factor, regulates energy homeostasis, and is involved in learning and memory acquisition. Many central nervous system (CNS) diseases are characterized by deficits in insulin signaling. Pre-clinical studies have shown that intranasal insulin is neuroprotective i...

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Detalles Bibliográficos
Autores principales: Lochhead, Jeffrey J., Kellohen, Kathryn L., Ronaldson, Patrick T., Davis, Thomas P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6385374/
https://www.ncbi.nlm.nih.gov/pubmed/30796294
http://dx.doi.org/10.1038/s41598-019-39191-5