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Distribution of insulin in trigeminal nerve and brain after intranasal administration
In the brain, insulin acts as a growth factor, regulates energy homeostasis, and is involved in learning and memory acquisition. Many central nervous system (CNS) diseases are characterized by deficits in insulin signaling. Pre-clinical studies have shown that intranasal insulin is neuroprotective i...
Autores principales: | Lochhead, Jeffrey J., Kellohen, Kathryn L., Ronaldson, Patrick T., Davis, Thomas P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6385374/ https://www.ncbi.nlm.nih.gov/pubmed/30796294 http://dx.doi.org/10.1038/s41598-019-39191-5 |
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