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Investigation of Permeation of Theophylline through Skin Using Selected Piperazine-2,5-Diones

Transdermal administration of drugs that penetrate, in this case directly into the blood circulation, has many advantages and is promising for many drugs thanks to its easy application and good patient compliance. (S)-8-Methyl-6,9-diazaspiro[4.5]decan-7,10-dione (alaptide), has been studied as a pot...

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Detalles Bibliográficos
Autores principales: Pokorna, Aneta, Bobal, Pavel, Oravec, Michal, Rarova, Lucie, Bobalova, Janette, Jampilek, Josef
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6385378/
https://www.ncbi.nlm.nih.gov/pubmed/30720734
http://dx.doi.org/10.3390/molecules24030566