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New combinatorial strategies to improve the PARP inhibitors efficacy in the urothelial bladder Cancer treatment
BACKGROUND: Novel therapeutic strategies are urgently needed for the treatment of metastatic Urothelial Bladder Cancer. DNA damaging repair (DDR) targeting has been introduced in cinical trials for bladder cancer patients that carry alterations in homologous DNA repair genes, letting to envisage sus...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6385418/ https://www.ncbi.nlm.nih.gov/pubmed/30791940 http://dx.doi.org/10.1186/s13046-019-1089-z |