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Combined analysis of dissimilar promoter accessibility and gene expression profiles identifies tissue-specific genes and actively repressed networks

BACKGROUND: The assay for transposase-accessible chromatin (ATAC-seq) is a powerful method to examine chromatin accessibility. While many studies have reported a positive correlation between gene expression and promoter accessibility, few have investigated the genes that deviate from this trend. In...

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Detalles Bibliográficos
Autores principales: Starks, Rebekah R., Biswas, Anilisa, Jain, Ashish, Tuteja, Geetu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6385419/
https://www.ncbi.nlm.nih.gov/pubmed/30795793
http://dx.doi.org/10.1186/s13072-019-0260-2