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LPCAT1 promotes brain metastasis of lung adenocarcinoma by up-regulating PI3K/AKT/MYC pathway

BACKGROUND: Brain metastasis (BM) is associated with poor prognosis, recurrence, and death in patients with non-small cell lung cancer (NSCLC). Lysophosphatidylcholine acyltransferase 1 (LPCAT1) has been reported to be involved in the progression, metastasis and recurrence of malignancies. However,...

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Detalles Bibliográficos
Autores principales: Wei, Chunhua, Dong, Xiaomin, Lu, Hui, Tong, Fan, Chen, Lingjuan, Zhang, Ruiguang, Dong, Jihua, Hu, Yu, Wu, Gang, Dong, Xiaorong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6385475/
https://www.ncbi.nlm.nih.gov/pubmed/30791942
http://dx.doi.org/10.1186/s13046-019-1092-4