Single Cell Profiling Reveals PTEN Overexpression in Influenza-Specific B cells in Aging HIV-infected individuals on Anti-retroviral Therapy

Memory B cells (MBC) respond to secondary antigen challenge to protect against infection and to boost immunity following vaccinations. Despite effective treatment, chronic HIV infection disturbs MBCs by reducing numbers and altering functionality due to hyper-activation and increased apoptosis leadi...

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Detalles Bibliográficos
Autores principales: de Armas, Lesley R., Pallikkuth, Suresh, Pan, Li, Rinaldi, Stefano, Cotugno, Nicola, Andrews, Sarah, Pahwa, Rajendra, McDermott, Adrian B., Palma, Paolo, Pahwa, Savita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6385500/
https://www.ncbi.nlm.nih.gov/pubmed/30792481
http://dx.doi.org/10.1038/s41598-019-38906-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6385500/
https://www.ncbi.nlm.nih.gov/pubmed/30792481
http://dx.doi.org/10.1038/s41598-019-38906-y

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