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A modular approach to prepare enantioenriched cyclobutanes: synthesis of (+)-rumphellaone A

A modular synthesis of enantioenriched polyfunctionalized cyclobutanes was developed that features an 8-aminoquinolinamide directed C–H arylation reaction. The C–H arylation products were derivatized through subsequent decarboxylative coupling processes. This synthetic strategy enabled a 9-step enan...

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Detalles Bibliográficos
Autores principales: Beck, Jordan C., Lacker, Caitlin R., Chapman, Lauren M., Reisman, Sarah E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6385545/
https://www.ncbi.nlm.nih.gov/pubmed/30881657
http://dx.doi.org/10.1039/c8sc05444d