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Bifunctional cleavable probes for in situ multiplexed glycan detection and imaging using mass spectrometry

In situ analysis of glycans is of great significance since they mediate a range of biological activities. Aberrant changes of glycosylation are closely related to cancer onset and progression. In this work, bifunctional laser cleavable mass probes (LCMPs) were developed for in situ glycan detection...

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Detalles Bibliográficos
Autores principales: Ma, Wen, Xu, Shuting, Nie, Honggang, Hu, Bingyang, Bai, Yu, Liu, Huwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6385553/
https://www.ncbi.nlm.nih.gov/pubmed/30881658
http://dx.doi.org/10.1039/c8sc04642e