(211)At-labeled immunoconjugate via a one-pot three-component double click strategy: practical access to α-emission cancer radiotherapeutics

α-Emission radiotherapeutics has potential to be one of most effective cancer therapeutics. Herein, we report a facile synthesis of an (211)At-labeled immunoconjugate for use as an α-emission molecular targeting therapy. We synthesized a tetrazine probe modified with closo-decaborate(2-), a prosthet...

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Detalles Bibliográficos
Autores principales: Fujiki, Katsumasa, Kanayama, Yousuke, Yano, Shinya, Sato, Nozomi, Yokokita, Takuya, Ahmadi, Peni, Watanabe, Yasuyoshi, Haba, Hiromitsu, Tanaka, Katsunori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2018
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6385556/
https://www.ncbi.nlm.nih.gov/pubmed/30881623
http://dx.doi.org/10.1039/c8sc04747b

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6385556/
https://www.ncbi.nlm.nih.gov/pubmed/30881623
http://dx.doi.org/10.1039/c8sc04747b

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