Cargando…

Loss of Platelet Endothelial Cell Adhesion Molecule-1 (PECAM-1) in the Diabetic Retina: Role of Matrix Metalloproteinases

PURPOSE: To test the hypothesis that high glucose and matrix metalloproteinases (MMPs) contribute to the diabetes-induced loss of platelet endothelial cell adhesion molecule-1 (PECAM-1) in the retinal microvasculature. METHODS: PECAM-1 and MMP protein, activity, and interactions with PECAM-1 were as...

Descripción completa

Detalles Bibliográficos
Autores principales:	Eshaq, Randa S., Harris, Norman R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Association for Research in Vision and Ophthalmology 2019
Materias:	Retina
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6385619/ https://www.ncbi.nlm.nih.gov/pubmed/30793207 http://dx.doi.org/10.1167/iovs.18-25068

Ejemplares similares

Vascular endothelial effects of collaborative binding to platelet/endothelial cell adhesion molecule-1 (PECAM-1)
por: Kiseleva, Raisa Yu., et al.
Publicado: (2018)

Monocarboxylate Transporter 1 (MCT1) Mediates Succinate Export in the Retina
por: Bisbach, Celia M., et al.
Publicado: (2022)

Integrin Activation by Regulated Dimerization and Oligomerization of Platelet Endothelial Cell Adhesion Molecule (Pecam)-1 from within the Cell
por: Zhao, Tieming, et al.
Publicado: (2001)

Soluble Domain 1 of Platelet–Endothelial Cell Adhesion Molecule (PECAM) Is Sufficient to Block Transendothelial Migration In Vitro and In Vivo
por: Liao, Fang, et al.
Publicado: (1997)

Differential effect of Platelet Endothelial Cell Adhesion Molecule-1 (PECAM-1) on leukocyte infiltration during contact hypersensitivity responses
por: Early, Merideth, et al.
Publicado: (2017)

CD40 Expressed in Endothelial Cells Promotes Upregulation of ICAM-1 But Not Pro-Inflammatory Cytokines, NOS2 and P2X(7) in the Diabetic Retina
por: Yu, Jin-Sang, et al.
Publicado: (2021)

Novel role of platelet endothelial cell adhesion molecule-1 (PECAM-1) in facilitating TGF-beta-mediated inhibition of T cell function
por: Newman, Debra, et al.
Publicado: (2015)

Lycium Barbarum Polysaccharides Protect Retina in rd1 Mice During Photoreceptor Degeneration
por: Liu, Feng, et al.
Publicado: (2018)

CD40 Upregulation in the Retina of Patients With Diabetic Retinopathy: Association With TRAF2/TRAF6 Upregulation and Inflammatory Molecule Expression
por: Vos, Sarah, et al.
Publicado: (2023)

Deletions in the cytoplasmic domain of platelet-endothelial cell adhesion molecule-1 (PECAM-1, CD31) result in changes in ligand binding properties
Publicado: (1994)

Ablation of Ctrp9, Ligand of AdipoR1, and Lower Number of Cone Photoreceptors in Mouse Retina
por: Inooka, Daiki, et al.
Publicado: (2022)

The Effects of Metformin on Obesity-Induced Dysfunctional Retinas
por: Kim, Andy Jeesu, et al.
Publicado: (2017)

Intravitreal AAV2.COMP-Ang1 Attenuates Deep Capillary Plexus Expansion in the Aged Diabetic Mouse Retina
por: Carroll, Lara S., et al.
Publicado: (2019)

The Retina in Alzheimer's Disease: Histomorphometric Analysis of an Ophthalmologic Biomarker
por: Asanad, Samuel, et al.
Publicado: (2019)

Metabolomics Analyses of Mouse Retinas in Oxygen-Induced Retinopathy
por: Zhou, Yedi, et al.
Publicado: (2021)

Diabetes Reshapes the Circadian Transcriptome Profile in Murine Retina
por: Ye, Suna, et al.
Publicado: (2023)

The exosome of platelet endothelial cell adhesion molecule-1 (PECAM1) protein: A potential risking star in high blood pressure patients (HBPP)
por: Zhu, Zhidong, et al.
Publicado: (2021)

Monomethyl Fumarate Protects the Retina From Light-Induced Retinopathy
por: Jiang, Dan, et al.
Publicado: (2019)

Elongation of the Retina and Ciliary Body in Dependence of the Sagittal Eye Diameter
por: Panda-Jonas, Songhomitra, et al.
Publicado: (2022)

Sortilin Inhibition Protects Neurons From Degeneration in the Diabetic Retina
por: Jakobsen, Thomas Stax, et al.
Publicado: (2023)

Evidence for Structural and Functional Damage of the Inner Retina in Diabetes With No Diabetic Retinopathy
por: Montesano, Giovanni, et al.
Publicado: (2021)

Tyrosine Residue in Exon 14 of the Cytoplasmic Domain of Platelet Endothelial Cell Adhesion Molecule-1 (PECAM-1/CD31) Regulates Ligand Binding Specificity
por: Famiglietti, Julie, et al.
Publicado: (1997)

Correlation of Optical Coherence Tomography and Autofluorescence in the Outer Retina and Choroid of Patients With Choroideremia
por: Xue, Kanmin, et al.
Publicado: (2016)

Imaging of Macrophage-Like Cells in Living Human Retina Using Clinical OCT
por: Castanos, Maria V., et al.
Publicado: (2020)

A Novel Device for Suprachoroidal Drug Delivery to Retina: Evaluation in Nonhuman Primates
por: Rotenstreich, Ygal, et al.
Publicado: (2023)

Sox2-Deficient Müller Glia Disrupt the Structural and Functional Maturation of the Mammalian Retina
por: Bachleda, Amelia R., et al.
Publicado: (2016)

Evaluating Signs of Microangiopathy Secondary to Diabetes in Different Areas of the Retina with Swept Source OCTA
por: Karst, Sonja G., et al.
Publicado: (2020)

Beneficial and Detrimental Pressure-Related Effects on Inner Neurons in the Adult Porcine In Vitro Retina
por: Svare, Frida, et al.
Publicado: (2023)

Assessment of the Retina of Plp-α-Syn Mice as a Model for Studying Synuclein-Dependent Diseases
por: Kaehler, Kathrin, et al.
Publicado: (2020)

Functional Correlates of Outer Retina Remodeling in Intermediate Age-Related Macular Degeneration Using Microperimetry
por: Fragiotta, Serena, et al.
Publicado: (2022)

Soluble platelet endothelial cell adhesion molecule 1 (sPECAM-1) improves diagnostic accuracy of D-Dimer in patients with suspected deep vein thrombosis (DVT)
por: Kellermair, Joerg, et al.
Publicado: (2020)

Expression of the SARS-CoV-2 Receptor ACE2 in Human Retina and Diabetes—Implications for Retinopathy
por: Zhou, Lingli, et al.
Publicado: (2021)

Ferritin But Not Iron Increases in Retina Upon Systemic Iron Overload in Diabetic and Iron-Dextran Injected Mice
por: Bonet, Aina, et al.
Publicado: (2023)

Retina
Publicado: (2005)

Diseases of the retina,/
por: Elwyn, Herman, b. 1887
Publicado: (1946)

Survey of the use of laser protective eyewear among international retina specialists: a European vitreoretinal society study
por: Siddiqui, Mohammad Z, et al.
Publicado: (2021)

Interobserver Agreement of Electrode to Retina Distance Measurements in a Second-Generation (44-Channel) Suprachoroidal Retinal Prosthesis
por: Abbott, Carla J., et al.
Publicado: (2022)

Rapamycin Inhibits Light-Induced Necrosome Activation Occurring in Wild-Type, but not RPE65-Null, Mouse Retina
por: Lu, Chunfeng, et al.
Publicado: (2022)

Surgically Induced Focal Retinal Detachment Does Not Cause Detectable SD-OCT Retinal Changes in Normal Human Retina
por: Kogachi, Kaitlin, et al.
Publicado: (2017)

Alterations in Tight- and Adherens-Junction Proteins Related to Glaucoma Mimicked in the Organotypically Cultivated Mouse Retina Under Elevated Pressure
por: Brockhaus, Katrin, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_omcrnln3pt3je6pj66vknloubq