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Impaired Glucocorticoid Suppression of TGFβ Signaling in Human Omental Adipose Tissues Limits Adipogenesis and May Promote Fibrosis

Visceral obesity is associated with insulin resistance and higher risk of type 2 diabetes and metabolic diseases. A limited ability of adipose tissues to remodel through the recruitment and differentiation of adipose stem cells (ASCs) is associated with adipose tissue inflammation and fibrosis and t...

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Detalles Bibliográficos
Autores principales: Lee, Mi-Jeong, Pickering, R. Taylor, Shibad, Varuna, Wu, Yuanyuan, Karastergiou, Kalypso, Jager, Mike, Layne, Matthew D., Fried, Susan K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6385749/
https://www.ncbi.nlm.nih.gov/pubmed/30530781
http://dx.doi.org/10.2337/db18-0955