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Impaired Glucocorticoid Suppression of TGFβ Signaling in Human Omental Adipose Tissues Limits Adipogenesis and May Promote Fibrosis
Visceral obesity is associated with insulin resistance and higher risk of type 2 diabetes and metabolic diseases. A limited ability of adipose tissues to remodel through the recruitment and differentiation of adipose stem cells (ASCs) is associated with adipose tissue inflammation and fibrosis and t...
Autores principales: | Lee, Mi-Jeong, Pickering, R. Taylor, Shibad, Varuna, Wu, Yuanyuan, Karastergiou, Kalypso, Jager, Mike, Layne, Matthew D., Fried, Susan K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Diabetes Association
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6385749/ https://www.ncbi.nlm.nih.gov/pubmed/30530781 http://dx.doi.org/10.2337/db18-0955 |
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