Loss of Nuclear and Membrane Estrogen Receptor-α Differentially Impairs Insulin Secretion and Action in Male and Female Mice

Estrogens favor glucose homeostasis primarily through the estrogen receptor-α (ERα), but the respective importance of nuclear ERα (NOER) and membrane ERα (MOER) pools to glucose homeostasis are unknown. We studied glucose homeostasis, insulin secretion, and insulin sensitivity in male and female mic...

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Detalles Bibliográficos
Autores principales: Allard, Camille, Morford, Jamie J., Xu, Beibei, Salwen, Benjamin, Xu, Weiwei, Desmoulins, Lucie, Zsombok, Andrea, Kim, Jason K., Levin, Ellis R., Mauvais-Jarvis, Franck
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2019
Materias:
Metabolism
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6385757/
https://www.ncbi.nlm.nih.gov/pubmed/30305367
http://dx.doi.org/10.2337/db18-0293

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6385757/
https://www.ncbi.nlm.nih.gov/pubmed/30305367
http://dx.doi.org/10.2337/db18-0293

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