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A Noisy Analog-to-Digital Converter Connects Cytosolic Calcium Bursts to Transcription Factor Nuclear Localization Pulses in Yeast

Several examples of transcription factors that show stochastic, unsynchronized pulses of nuclear localization have been described. Here we show that under constant calcium stress, nuclear localization pulses of the transcription factor Crz1 follow stochastic variations in cytosolic calcium concentra...

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Detalles Bibliográficos
Autores principales: Hsu, Ian S., Strome, Bob, Plotnikov, Sergey, Moses, Alan M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6385971/
https://www.ncbi.nlm.nih.gov/pubmed/30573469
http://dx.doi.org/10.1534/g3.118.200841