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Generation of H11-albumin-rtTA Transgenic Mice: A Tool for Inducible Gene Expression in the Liver

The modification of the mouse genome by site-specific gene insertion of transgenes and other genetic elements allows the study of gene function in different developmental stages and in the pathogenesis of diseases. Here, we generated a “genomic safe harbor” Hipp11 (H11) locus-specific knock-in trans...

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Detalles Bibliográficos
Autores principales: Li, Yu-Shan, Meng, Ran-Ran, Chen, Xiu, Shang, Cui-Ling, Li, Hong-Bin, Zhang, Tao-Jun, Long, Hua-Yang, Li, Hui-Qi, Wang, Yi-Jing, Wang, Feng-Chao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6385985/
https://www.ncbi.nlm.nih.gov/pubmed/30591434
http://dx.doi.org/10.1534/g3.118.200963