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The Crohn’s disease associated SNP rs6651252 impacts MYC gene expression in human colonic epithelial cells

Crohn’s disease (CD) is a debilitating inflammatory bowel disease (IBD) that arises from chronic inflammation in the gastrointestinal tract. Genome-wide association studies (GWAS) have identified over 200 single nucleotide polymorphisms (SNPs) that are associated with a predisposition for developing...

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Detalles Bibliográficos
Autores principales: Matthews, Stephen M., Eshelman, Melanie A., Berg, Arthur S., Koltun, Walter A., Yochum, Gregory S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6386311/
https://www.ncbi.nlm.nih.gov/pubmed/30794691
http://dx.doi.org/10.1371/journal.pone.0212850