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HBV preS deletion mapping using deep sequencing demonstrates a unique association with viral markers

AIM: Deletions are observed frequently in the preS1/S2 region of hepatitis B virus (HBV) genome, in association with liver disease advancement. However, the most significant preS1/S2 region and its influences on viral markers are unclear. METHODS: The preS1/S2 HBV regions of 90 patients without anti...

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Detalles Bibliográficos
Autores principales: Suzuki, Yuichiro, Maekawa, Shinya, Komatsu, Nobutoshi, Sato, Mitsuaki, Tatsumi, Akihisa, Miura, Mika, Matsuda, Shuya, Muraoka, Masaru, Nakakuki, Natsuko, Amemiya, Fumitake, Takano, Shinichi, Fukasawa, Mitsuharu, Nakayama, Yasuhiro, Yamaguchi, Tatsuya, Inoue, Taisuke, Sato, Tadashi, Sakamoto, Minoru, Yamashita, Atsuya, Moriishi, Kohji, Enomoto, Nobuyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6386350/
https://www.ncbi.nlm.nih.gov/pubmed/30794632
http://dx.doi.org/10.1371/journal.pone.0212559