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Network-guided prediction of aromatase inhibitor response in breast cancer

Prediction of response to specific cancer treatments is complicated by significant heterogeneity between tumors in terms of mutational profiles, gene expression, and clinical measures. Here we focus on the response of Estrogen Receptor (ER)+ post-menopausal breast cancer tumors to aromatase inhibito...

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Detalles Bibliográficos
Autores principales: Ruffalo, Matthew, Thomas, Roby, Chen, Jian, Lee, Adrian V., Oesterreich, Steffi, Bar-Joseph, Ziv
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6386390/
https://www.ncbi.nlm.nih.gov/pubmed/30742607
http://dx.doi.org/10.1371/journal.pcbi.1006730