Cargando…
Broad antifungal resistance mediated by RNAi-dependent epimutation in the basal human fungal pathogen Mucor circinelloides
Mucormycosis—an emergent, deadly fungal infection—is difficult to treat, in part because the causative species demonstrate broad clinical antifungal resistance. However, the mechanisms underlying drug resistance in these infections remain poorly understood. Our previous work demonstrated that one ma...
Autores principales: | Chang, Zanetta, Billmyre, R. Blake, Lee, Soo Chan, Heitman, Joseph |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6386414/ https://www.ncbi.nlm.nih.gov/pubmed/30742617 http://dx.doi.org/10.1371/journal.pgen.1007957 |
Ejemplares similares
-
A non-canonical RNA degradation pathway suppresses RNAi-dependent epimutations in the human fungal pathogen Mucor circinelloides
por: Calo, Silvia, et al.
Publicado: (2017) -
Drug-Resistant Epimutants Exhibit Organ-Specific Stability and Induction during Murine Infections Caused by the Human Fungal Pathogen Mucor circinelloides
por: Chang, Zanetta, et al.
Publicado: (2019) -
A Novel Resistance Pathway for Calcineurin Inhibitors in the Human-Pathogenic Mucorales Mucor circinelloides
por: Vellanki, Sandeep, et al.
Publicado: (2020) -
Analysis of a Food-Borne Fungal Pathogen Outbreak: Virulence and Genome of a Mucor circinelloides Isolate from Yogurt
por: Lee, Soo Chan, et al.
Publicado: (2014) -
The RNAi machinery controls distinct responses to environmental signals in the basal fungus Mucor circinelloides
por: Nicolás, Francisco E, et al.
Publicado: (2015)