Mitochondrial proline catabolism activates Ras1/cAMP/PKA-induced filamentation in Candida albicans

Amino acids are among the earliest identified inducers of yeast-to-hyphal transitions in Candida albicans, an opportunistic fungal pathogen of humans. Here, we show that the morphogenic amino acids arginine, ornithine and proline are internalized and metabolized in mitochondria via a PUT1- and PUT2-...

Descripción completa

Detalles Bibliográficos
Autores principales: Silao, Fitz Gerald S., Ward, Meliza, Ryman, Kicki, Wallström, Axel, Brindefalk, Björn, Udekwu, Klas, Ljungdahl, Per O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6386415/
https://www.ncbi.nlm.nih.gov/pubmed/30742618
http://dx.doi.org/10.1371/journal.pgen.1007976

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6386415/
https://www.ncbi.nlm.nih.gov/pubmed/30742618
http://dx.doi.org/10.1371/journal.pgen.1007976

Ejemplares similares