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Mitochondrial proline catabolism activates Ras1/cAMP/PKA-induced filamentation in Candida albicans
Amino acids are among the earliest identified inducers of yeast-to-hyphal transitions in Candida albicans, an opportunistic fungal pathogen of humans. Here, we show that the morphogenic amino acids arginine, ornithine and proline are internalized and metabolized in mitochondria via a PUT1- and PUT2-...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6386415/ https://www.ncbi.nlm.nih.gov/pubmed/30742618 http://dx.doi.org/10.1371/journal.pgen.1007976 |