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Comparative purification and characterization of hepatitis B virus-like particles produced by recombinant vaccinia viruses in human hepatoma cells and human primary hepatocytes

This study describes the comparative expression and purification of hepatitis B surface antigen (HBsAg) particles produced upon infection of human primary hepatocytes and human hepatoma cell lines (HuH-7 and HepG2) with recombinant vaccinia viruses. The highest levels of HBsAg expression were found...

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Detalles Bibliográficos
Autores principales: Reuschel, Edith, Jilg, Wolfgang, Seelbach-Goebel, Birgit, Deml, Ludwig
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6386438/
https://www.ncbi.nlm.nih.gov/pubmed/30794666
http://dx.doi.org/10.1371/journal.pone.0212800