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Chromatin accessibility pre-determines glucocorticoid receptor binding patterns

Development, differentiation, and response to environmental stimuli are characterized by sequential changes in cellular state initiated by the de novo binding of regulated transcriptional factors to their cognate genomic sites 1,2,3. The mechanism whereby a given regulatory factor selects a limited...

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Detalles Bibliográficos
Autores principales: John, Sam, Sabo, Peter J., Thurman, Robert E., Sung, Myong-Hee, Biddie, Simon C., Johnson, Thomas A., Hager, Gordon L., Stamatoyannopoulos, John A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6386452/
https://www.ncbi.nlm.nih.gov/pubmed/21258342
http://dx.doi.org/10.1038/ng.759