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Structural insights into the inhibition properties of archaeon citrate synthase from Metallosphaera sedula

Metallosphaera sedula is a thermoacidophilic archaeon and has an incomplete TCA/glyoxylate cycle that is used for production of biosynthetic precursors of essential metabolites. Citrate synthase from M. sedula (MsCS) is an enzyme involved in the first step of the incomplete TCA/glyoxylate cycle by c...

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Detalles Bibliográficos
Autores principales: Lee, Seul Hoo, Son, Hyeoncheol Francis, Kim, Kyung-Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6386500/
https://www.ncbi.nlm.nih.gov/pubmed/30794680
http://dx.doi.org/10.1371/journal.pone.0212807