Reactivation of a developmental Bmp2 signaling center is required for therapeutic control of the murine periosteal niche

Two decades after signals controlling bone length were discovered, the endogenous ligands determining bone width remain unknown. We show that postnatal establishment of normal bone width in mice, as mediated by bone-forming activity of the periosteum, requires BMP signaling at the innermost layer of...

Descripción completa

Detalles Bibliográficos
Autores principales: Salazar, Valerie S, Capelo, Luciane P, Cantù, Claudio, Zimmerli, Dario, Gosalia, Nehal, Pregizer, Steven, Cox, Karen, Ohte, Satoshi, Feigenson, Marina, Gamer, Laura, Nyman, Jeffry S, Carey, David J, Economides, Aris, Basler, Konrad, Rosen, Vicki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2019
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6386520/
https://www.ncbi.nlm.nih.gov/pubmed/30735122
http://dx.doi.org/10.7554/eLife.42386

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6386520/
https://www.ncbi.nlm.nih.gov/pubmed/30735122
http://dx.doi.org/10.7554/eLife.42386

Ejemplares similares