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Reactivation of a developmental Bmp2 signaling center is required for therapeutic control of the murine periosteal niche
Two decades after signals controlling bone length were discovered, the endogenous ligands determining bone width remain unknown. We show that postnatal establishment of normal bone width in mice, as mediated by bone-forming activity of the periosteum, requires BMP signaling at the innermost layer of...
Autores principales: | Salazar, Valerie S, Capelo, Luciane P, Cantù, Claudio, Zimmerli, Dario, Gosalia, Nehal, Pregizer, Steven, Cox, Karen, Ohte, Satoshi, Feigenson, Marina, Gamer, Laura, Nyman, Jeffry S, Carey, David J, Economides, Aris, Basler, Konrad, Rosen, Vicki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6386520/ https://www.ncbi.nlm.nih.gov/pubmed/30735122 http://dx.doi.org/10.7554/eLife.42386 |
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