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Optical manipulation of sphingolipid biosynthesis using photoswitchable ceramides

Ceramides are central intermediates of sphingolipid metabolism that also function as potent messengers in stress signaling and apoptosis. Progress in understanding how ceramides execute their biological roles is hampered by a lack of methods to manipulate their cellular levels and metabolic fate wit...

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Detalles Bibliográficos
Autores principales: Kol, Matthijs, Williams, Ben, Toombs-Ruane, Henry, Franquelim, Henri G, Korneev, Sergei, Schroeer, Christian, Schwille, Petra, Trauner, Dirk, Holthuis, Joost CM, Frank, James A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6386522/
https://www.ncbi.nlm.nih.gov/pubmed/30720434
http://dx.doi.org/10.7554/eLife.43230