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Optical manipulation of sphingolipid biosynthesis using photoswitchable ceramides
Ceramides are central intermediates of sphingolipid metabolism that also function as potent messengers in stress signaling and apoptosis. Progress in understanding how ceramides execute their biological roles is hampered by a lack of methods to manipulate their cellular levels and metabolic fate wit...
Autores principales: | Kol, Matthijs, Williams, Ben, Toombs-Ruane, Henry, Franquelim, Henri G, Korneev, Sergei, Schroeer, Christian, Schwille, Petra, Trauner, Dirk, Holthuis, Joost CM, Frank, James A |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6386522/ https://www.ncbi.nlm.nih.gov/pubmed/30720434 http://dx.doi.org/10.7554/eLife.43230 |
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