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Systematic review and meta-analysis of experimental studies evaluating the organ protective effects of histone deacetylase inhibitors

The clinical efficacy of organ protection interventions are limited by the redundancy of cellular activation mechanisms. Interventions that target epigenetic mechanisms overcome this by eliciting genome wide changes in transcription and signaling. We aimed to review preclinical studies evaluating th...

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Detalles Bibliográficos
Autores principales: Yusoff, Syabira I., Roman, Marius, Lai, Florence Y., Eagle-Hemming, Bryony, Murphy, Gavin J., Kumar, Tracy, Wozniak, Marcin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6386580/
https://www.ncbi.nlm.nih.gov/pubmed/30528323
http://dx.doi.org/10.1016/j.trsl.2018.11.002