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Systematic review and meta-analysis of experimental studies evaluating the organ protective effects of histone deacetylase inhibitors
The clinical efficacy of organ protection interventions are limited by the redundancy of cellular activation mechanisms. Interventions that target epigenetic mechanisms overcome this by eliciting genome wide changes in transcription and signaling. We aimed to review preclinical studies evaluating th...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6386580/ https://www.ncbi.nlm.nih.gov/pubmed/30528323 http://dx.doi.org/10.1016/j.trsl.2018.11.002 |