Molecular basis for AU-rich element recognition and dimerization by the HuR C-terminal RRM

Human antigen R (HuR) is a key regulator of cellular mRNAs containing adenylate/uridylate–rich elements (AU-rich elements; AREs). These are a major class of cis elements within 3′ untranslated regions, targeting these mRNAs for rapid degradation. HuR contains three RNA recognition motifs (RRMs): a t...

Descripción completa

Detalles Bibliográficos
Autores principales: Ripin, Nina, Boudet, Julien, Duszczyk, Malgorzata M., Hinniger, Alexandra, Faller, Michael, Krepl, Miroslav, Gadi, Abhilash, Schneider, Robert J., Šponer, Jiří, Meisner-Kober, Nicole C., Allain, Frédéric H.-T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2019
Materias:
PNAS Plus
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6386705/
https://www.ncbi.nlm.nih.gov/pubmed/30718402
http://dx.doi.org/10.1073/pnas.1808696116

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6386705/
https://www.ncbi.nlm.nih.gov/pubmed/30718402
http://dx.doi.org/10.1073/pnas.1808696116

Ejemplares similares