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Tumor-derived exosomal HMGB1 promotes esophageal squamous cell carcinoma progression through inducing PD1(+) TAM expansion

Macrophages constitute one of the most common components of immune cells, which penetrate tumors and they have a key role in tumor prognosis. Here, we identified an unrecognized macrophage subpopulation, which favors tumorigenesis. These macrophages express programmed cell death protein 1 (PD1) in a...

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Detalles Bibliográficos
Autores principales: Li, Bin, Song, Tie-Niu, Wang, Fu-Rong, Yin, Ci, Li, Zheng, Lin, Jun-Ping, Meng, Yu-Qi, Feng, Hai-Ming, Jing, Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6386749/
https://www.ncbi.nlm.nih.gov/pubmed/30796203
http://dx.doi.org/10.1038/s41389-019-0126-2