Characterization of recombinant fructose-1,6-bisphosphatase gene mutations: evidence of inhibition/activation of FBPase protein by gene mutation

Specific residues of the highly regulated fructose-1,6-bisphosphatase (FBPase) enzyme serve as important contributors to the catalytic activity of the enzyme. Previous clinical studies exploring the genetic basis of hypoglycemia revealed two significant mutations in the coding region of the FBPase g...

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Detalles Bibliográficos
Autores principales: Topaz, Gemma, Epiter-Smith, Victor, Robalo, Cristina, Emad, Megan, Ford, Vanessa, Daley, Jadine, Byron, Jennifer, Stieglitz, Kimberly A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2019
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6386767/
https://www.ncbi.nlm.nih.gov/pubmed/30683805
http://dx.doi.org/10.1042/BSR20180960

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6386767/
https://www.ncbi.nlm.nih.gov/pubmed/30683805
http://dx.doi.org/10.1042/BSR20180960

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