GPR68: An Emerging Drug Target in Cancer

GPR68 (or ovarian cancer G protein-coupled receptor 1, OGR1) is a proton-sensing G-protein-coupled receptor (GPCR) that responds to extracellular acidity and regulates a variety of cellular functions. Acidosis is considered a defining hallmark of the tumor microenvironment (TME). GPR68 expression is...

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Detalles Bibliográficos
Autores principales: Wiley, Shu Z., Sriram, Krishna, Salmerón, Cristina, Insel, Paul A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6386835/
https://www.ncbi.nlm.nih.gov/pubmed/30696114
http://dx.doi.org/10.3390/ijms20030559

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6386835/
https://www.ncbi.nlm.nih.gov/pubmed/30696114
http://dx.doi.org/10.3390/ijms20030559

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