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GPR68: An Emerging Drug Target in Cancer
GPR68 (or ovarian cancer G protein-coupled receptor 1, OGR1) is a proton-sensing G-protein-coupled receptor (GPCR) that responds to extracellular acidity and regulates a variety of cellular functions. Acidosis is considered a defining hallmark of the tumor microenvironment (TME). GPR68 expression is...
Autores principales: | Wiley, Shu Z., Sriram, Krishna, Salmerón, Cristina, Insel, Paul A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6386835/ https://www.ncbi.nlm.nih.gov/pubmed/30696114 http://dx.doi.org/10.3390/ijms20030559 |
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