Exosomal Expression of CXCR4 Targets Cardioprotective Vesicles to Myocardial Infarction and Improves Outcome after Systemic Administration

Cell therapy has been evaluated to enhance heart function after injury. Delivered cells mostly act via paracrine mechanisms, including secreted growth factors, cytokines, and vesicles, such as exosomes (Exo). Intramyocardial injection of cardiac-resident progenitor cells (CPC)-derived Exo reduced sc...

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Detalles Bibliográficos
Autores principales: Ciullo, Alessandra, Biemmi, Vanessa, Milano, Giuseppina, Bolis, Sara, Cervio, Elisabetta, Fertig, Emanuel Tudor, Gherghiceanu, Mihaela, Moccetti, Tiziano, Camici, Giovanni G., Vassalli, Giuseppe, Barile, Lucio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6386845/
https://www.ncbi.nlm.nih.gov/pubmed/30678240
http://dx.doi.org/10.3390/ijms20030468

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6386845/
https://www.ncbi.nlm.nih.gov/pubmed/30678240
http://dx.doi.org/10.3390/ijms20030468

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