Cargando…
Structural Perspective on Revealing and Altering Molecular Functions of Genetic Variants Linked with Diseases
Structural information of biological macromolecules is crucial and necessary to deliver predictions about the effects of mutations—whether polymorphic or deleterious (i.e., disease causing), wherein, thermodynamic parameters, namely, folding and binding free energies potentially serve as effective b...
| Autores principales: | , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2019
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6386852/ https://www.ncbi.nlm.nih.gov/pubmed/30696058 http://dx.doi.org/10.3390/ijms20030548 |