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Drug Development for Alzheimer’s Disease: Microglia Induced Neuroinflammation as a Target?

Alzheimer’s disease (AD) is one of the most common causes of dementia. Its pathogenesis is characterized by the aggregation of the amyloid-β (Aβ) protein in senile plaques and the hyperphosphorylated tau protein in neurofibrillary tangles in the brain. Current medications for AD can provide temporar...

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Detalles Bibliográficos
Autores principales: Dong, Yuan, Li, Xiaoheng, Cheng, Jinbo, Hou, Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6386861/
https://www.ncbi.nlm.nih.gov/pubmed/30696107
http://dx.doi.org/10.3390/ijms20030558