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Drug Development for Alzheimer’s Disease: Microglia Induced Neuroinflammation as a Target?
Alzheimer’s disease (AD) is one of the most common causes of dementia. Its pathogenesis is characterized by the aggregation of the amyloid-β (Aβ) protein in senile plaques and the hyperphosphorylated tau protein in neurofibrillary tangles in the brain. Current medications for AD can provide temporar...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6386861/ https://www.ncbi.nlm.nih.gov/pubmed/30696107 http://dx.doi.org/10.3390/ijms20030558 |