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Kaempferol Attenuates LPS-Induced Striatum Injury in Mice Involving Anti-Neuroinflammation, Maintaining BBB Integrity, and Down-Regulating the HMGB1/TLR4 Pathway

Neuroinflammation has been demonstrated to be linked with Parkinson’s disease (PD), Alzheimer’s disease, and cerebral ischemia. Our previous investigation had identified that kaempferol (KAE) exerted protective effects on cortex neuron injured by LPS. In this study, the effects and possible mechanis...

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Detalles Bibliográficos
Autores principales: Yang, Ying-Lin, Cheng, Xiao, Li, Wei-Han, Liu, Man, Wang, Yue-Hua, Du, Guan-Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6386879/
https://www.ncbi.nlm.nih.gov/pubmed/30678325
http://dx.doi.org/10.3390/ijms20030491