Identification of a Novel Quinoxaline-Isoselenourea Targeting the STAT3 Pathway as a Potential Melanoma Therapeutic

The prognosis for patients with metastatic melanoma remains very poor. Constitutive signal transducer and activator of transcription 3 (STAT3) activation has been correlated to metastasis, poor patient survival, larger tumor size, and acquired resistance against vemurafenib (PLX-4032), suggesting it...

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Detalles Bibliográficos
Autores principales: Alcolea, Verónica, Karelia, Deepkamal N., Pandey, Manoj K., Plano, Daniel, Singh, Parvesh, Palop, Juan Antonio, Amin, Shantu, Sanmartín, Carmen, Sharma, Arun K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6386884/
https://www.ncbi.nlm.nih.gov/pubmed/30691132
http://dx.doi.org/10.3390/ijms20030521

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6386884/
https://www.ncbi.nlm.nih.gov/pubmed/30691132
http://dx.doi.org/10.3390/ijms20030521

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