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Thioridazine Enhances P62-Mediated Autophagy and Apoptosis Through Wnt/β-Catenin Signaling Pathway in Glioma Cells

Thioridazine (THD) is a common phenothiazine antipsychotic drug reported to suppress growth in several types of cancer cells. We previously showed that THD acts as an antiglioblastoma and anticancer stem-like cell agent. However, the signaling pathway underlying autophagy and apoptosis induction rem...

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Detalles Bibliográficos
Autores principales: Chu, Cheng-Wei, Ko, Huey-Jiun, Chou, Chia-Hua, Cheng, Tai-Shan, Cheng, Hui-Wen, Liang, Yu-Hsin, Lai, Yun-Ling, Lin, Chen-Yen, Wang, Chihuei, Loh, Joon-Khim, Cheng, Jiin-Tsuey, Chiou, Shean-Jaw, Su, Chun-Li, Huang, Chi-Ying F., Hong, Yi-Ren
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6386927/
https://www.ncbi.nlm.nih.gov/pubmed/30678307
http://dx.doi.org/10.3390/ijms20030473